NEW CRYSTAL-STRUCTURES OF NUCLEIC-ACIDS AND THEIR COMPLEXES

In the past year, X-ray crystallographic studies of representatives of all nucleic acid structural types have been reported. Among the most interesting structures are the parallel DNA tetraplex formed by d(TGGG GT), the four-stranded structure formed by d(CCCT) and a double drug b ound side by side in an antiparallel orientation to the minor groove o f a B-DNA. Certainly, the structure that has received most attention i s that of the first complex of a ribozyme with an inhibitor DNA.