POLYFUNCTIONAL INDOLE-3-CARBINOL DERIVATIVES - 1-(INDOL-3-YL)GLYCEROLS AND RELATED-COMPOUNDS, BETA-HYDROXYTRYPTAMINES AND ASCORBIGENS - CHEMISTRY AND BIOLOGICAL PROPERTIES

Authors
PREOBRAZHENSKAYA MN KOROLEV AM ISAEVA NN LAZHKO EI LOMIDZE LA
Citation
Mn. Preobrazhenskaya et al., POLYFUNCTIONAL INDOLE-3-CARBINOL DERIVATIVES - 1-(INDOL-3-YL)GLYCEROLS AND RELATED-COMPOUNDS, BETA-HYDROXYTRYPTAMINES AND ASCORBIGENS - CHEMISTRY AND BIOLOGICAL PROPERTIES, Il Farmaco, 50(6), 1995, pp. 369-377
Citations number
34
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Il Farmaco → ACNP
ISSN journal
0014827X
Volume
50
Issue
6
Year of publication
1995
Pages
369 - 377
Database
ISI
SICI code
0014-827X(1995)50:6<369:PID-1>2.0.ZU;2-O
Abstract
Earlier interaction of indole-3-carbinols with L-ascorbic acid and che mical and biological properties of formed 2-skatylderivatives of L-asc orbic acid (ascorbigens) were discussed. In this presentation the prop erties and stereochemistry of products of interaction of polyfunctiona l biologically important indole-3-carbinols (indoleglycerol analogs an d beta-hydroxytryptamine derivatives) with L-ascorbic acid are investi gated. Biological significance of this reaction is discussed.