Background: Although transesophageal echocardiography allows continuou
s intraoperative cardiac monitoring, the technique has been limited by
the lack of a method for realtime, quantitative assessment of cardiac
chamber size and systolic function. Automated border detection (ABD),
based on an analysis of integrated backscatter, is a new technique th
at is purported to provide real-time, quantitative assessment of left
ventricular (LV) areas and fractional area change (FAG). A prospective
investigation was designed to assess the accuracy and trending capabi
lity of ABD during continuous intraoperative monitoring. Methods: In 1
6 patients monitored throughout noncardiac surgical procedures, serial
real-time estimates of LV end-diastolic area (EDA), end-systolic area
(ESA), and FAC by ABD were compared with paired off-line manual measu
rements made by two experienced echocardiographers. Results: There was
a high correlation between real-time ABD estimates of LV ESA (r = 0.9
3), EDA (r = 0.89), and FAC (r = 0.90) to those of the off-line techni
que. The automated technique systematically underestimated both EDA an
d ESA, resulting in a small underestimation of FAG. The automated tech
nique demonstrated an accuracy rate of 96% in tracking serial changes
in LV area, The technique performed with an 83% sensitivity and 85% sp
ecificity for detecting acute changes in LV area, Conclusions: This an
alysis of serial intraoperative echocardiograms demonstrates the accur
acy of ABD to estimate LV area in real time and to track serial change
s in cardiac area during surgery. Although ABD is an automated techniq
ue, application by personnel experienced in its operation and an echoc
ardiographic system that includes lateral-gain adjustment controls are
recommended for its optimal performance.