SINUS HISTIOCYTOSIS CONFINED TO THE SKIN - CASE-REPORT AND REVIEW OF THE LITERATURE

Sinus histiocytosis with massive lymphadenopathy is an uncommon diseas e affecting individuals of either sex and of all ages and ethnic backg rounds. We present a case of sinus histiocytosis confined to the skin in a 65-year-old woman whose diagnosis was coincident with herpes simp lex virus infection and polybacterial urinary infection, both asymptom atic. The polymerase chain reaction for herpes simplex virus and human herpesvirus-6 from involved skin was negative. We review previously p ublished cases of sinus histiocytosis limited to the skin.