We present results from a simulation study for the estimation of a com
mon odds ratio in multiple 2 x 2 tables when the data are correlated w
ithin clusters. We model the correlation of the data by the beta-binom
ial distribution. Through a simulation study, we compare the Mantel-Ha
enszel estimator with Rao and Scott's estimator in terms of their bias
es, observed variances, relative efficiencies of their variances and 9
5 per cent coverage proportions. We limit the simulation study to the
case where there are the same number of subjects in each cluster and t
he same number of observations in each raw of each stratum. When rho =
0, we recommend use of the Mantel-Haenszel estimator gamma(MH) with a
n unadjusted variance and Rao and Scott's estimator gamma(RS)(P) with
a pooled design effect. In general, when rho > 0, we recommend the Man
tel-Haenszel estimator gamma(MH) with an adjusted variance and Rao and
Scott's estimator gamma(RS)(P) with a pooled design effect.