DETERMINATION OF A CARDIAC ANTIARRHYTHMIC, TRICYCLIC ANTIPSYCHOTICS AND ANTIDEPRESSANTS IN HUMAN AND ANIMAL URINE BY MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY USING A BILE-SALT

Authors
AUMATELL A WELLS RJ
Citation
A. Aumatell et Rj. Wells, DETERMINATION OF A CARDIAC ANTIARRHYTHMIC, TRICYCLIC ANTIPSYCHOTICS AND ANTIDEPRESSANTS IN HUMAN AND ANIMAL URINE BY MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY USING A BILE-SALT, Journal of chromatography B. Biomedical applications, 669(2), 1995, pp. 331-344
Citations number
30
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Journal of chromatography B. Biomedical applications
ISSN journal
15726495 → ACNP
Volume
669
Issue
2
Year of publication
1995
Pages
331 - 344
Database
ISI
SICI code
Abstract
A micellar electrokinetic capillary chromatographic method based on th e use of sodium taurodeoxycholate has been developed to detect and qua ntitate a total of 26 tricyclic drugs. Detection limits in urine down to 4 ng/ml have been obtained. The method uses a simple liquid-liquid extraction and recovery of analytes followed by ultraviolet detection.