CONDITIONED MEDIUM FROM A CELL STRAIN DERIVED FROM A PATIENT WITH MASTOCYTOSIS INDUCES THE DEVELOPMENT OF MATURE HUMAN MAST-CELLS IN-VITRO FROM NORMAL HUMAN BONE-MARROW

Mature human mast cells were obtained from human bone marrow in a cocu lture system using conditioned medium from a human mastocytosis cell s train, These cells expressed the high-affinity IgE receptor and were t ryptase, chymase and carboxypeptidase positive.