The search for a pacemaker that accurately and easily mimics normal ph
ysiology is a continuing effort. Present pacing developments include A
V synchrony and rate adaptiveness. The usefulness and clinical value o
f some of the new pacing systems remain unclear. Although the hemodyna
mic advantages of rate responsive pacing over classical ventricular pa
cing are well established (Kristensson et al., 1985), an ideal sensor
for physiological demands has not been established. We report a case o
f apparently unequivocal increase in heart rate during upper limb move
ments in a patient with a VVI-R pacemaker using minute ventilation as
a sensor. Inappropriate heart rate acceleration may result from change
s in transthoracic impedance due to upper limb exercise and it does no
t necessarily represent sensor malfunction. Although this complication
is well-known in VVI-R pacemakers using respiratory rate or minute ve
ntilation as sensor (Santomauro et al., 1992), one must remain aware o
f this sensor-related problem. In this particular patient the problem
could be solved by implanting the pacemaker can more medially.