Ga. Decarli et al., DETERMINATION OF HEMOLYTIC-ACTIVITY OF DIFFERENT STRAINS OF TRICHOMONADS OF GENUS TRICHOMONAS DONNE, 1836 AND TRITRICHOMONAS KOFOID, 1920, Journal of protozoology research, 4(4), 1994, pp. 158-163
The hemolytic activity of live Trichomonas vaginalis, Trichomonas gall
inae, Tritrichomonas foetus, Tritrichomonas suis was described. The fo
ur isolates were tested against human erythrocytes. No hemolytic activ
ity was detected by the isolates of genus Tritrichomonas. Whereas the
strains of genus Trichomonas lysed all human blood groups. No hemolysi
n released by the parasites could be detected. Our preliminary results
suggest that the hemolysis depends on the susceptibility of red cell
membranes to destabilization and the intervention of cell surface rece
ptors as a mechanism of the hemolytic activity. This mechanism could b
e subject to strain-genera-species specific variation of trichomonads.
Although the hemolytic activity of T. vaginalis and T. gallinae is no
t due to a hemolysin or to a product of its metabolism. Pre-treatment
of trichomonads with concanavalin A reduced levels of hemolysis by 40%
.