A single evader attempts to traverse a path between two nodes in a net
work while a single interdictor attempts to detect the evader by setti
ng up an inspection point along one of the network arcs. For each are
there is a known probability of detection if the evader traverses the
are that the interdictor is inspecting. The evader must determine a pr
obabilistic ''path-selection'' strategy which minimizes the probabilit
y of detection while the interdictor must determine a probabilistic ''
arc-inspection'' strategy which maximizes the probability of detection
. The interdictor represents, in a simplified form, U.S. and allied fo
rces attempting to interdict drugs and precursor chemicals as they are
moved through river, road, and air routes in Latin America and the Ca
ribbean. We show that the basic scenario is a two-person zero-sum game
that might require the enumeration of an exponential number of paths,
but then show that optimal strategies can be found using network how
techniques of polynomial complexity. To enhance realism, we also solve
problems with unknown origins and destinations, multiple interdictors
or evaders, and other generalizations.