An actinomycete, designated strain KS3-5, was isolated from a soil sam
ple collected from Kaohsiung, Taiwan, ROC. This organism is capable of
producing a series of antibiotics that strongly inhibit the growth of
Gram-positive and Gram-negative bacteria and yeast-like fungi. The sp
ore morphology and cell wall chemotype suggest that strain KS3-5 is a
streptomycete. Further cultural and physiological characterization and
the DNA homology suggest that strain KS3-5 is identical to Streptomyc
es toxytricini.