DESIGN, SYNTHESIS AND X-RAY CRYSTALLOGRAPHIC STUDIES OF NOVEL FKBP-12LIGANDS

Authors
BABINE RE BLECKMAN TM KISSINGER CR SHOWALTER R PELLETIER LA LEWIS C TUCKER K MOOMAW E PARGE HE VILLAFRANCA JE
Citation
Re. Babine et al., DESIGN, SYNTHESIS AND X-RAY CRYSTALLOGRAPHIC STUDIES OF NOVEL FKBP-12LIGANDS, Bioorganic & medicinal chemistry letters, 5(15), 1995, pp. 1719-1724
Citations number
29
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
15
Year of publication
1995
Pages
1719 - 1724
Database
ISI
SICI code
0960-894X(1995)5:15<1719:DSAXCS>2.0.ZU;2-T
Abstract
Using the crystal structure of FKBP-12 a novel class of ligands were d esigned, prepared and evaluated. The crystal structure of the complex between 5 and FKBP-12 is reported.