C. Griep et al., ELECTRON-BEAM THERAPY IS NOT INFERIOR TO SUPERFICIAL X-RAY THERAPY INTHE TREATMENT OF SKIN CARCINOMA, International journal of radiation oncology, biology, physics, 32(5), 1995, pp. 1347-1350
Citations number
10
Categorie Soggetti
Oncology,"Radiology,Nuclear Medicine & Medical Imaging
Purpose: To compare recurrence rates and cosmetic results after electr
on beam therapy vs, superficial xray therapy for nonmelanoma skin carc
inoma. Methods and Materials: A retrospective analysis was performed o
n 389 histologically confirmed basal cell and squamous cell carcinomas
of the skin, treated with either superficial x-rays or electron beam
therapy, with regard to local control rates and cosmetics, as scored w
ith an arbitrary three-point scale. Results: The overall local recurre
nce rate was 4.9% (19 out of 389), For small tumors (irradiated surfac
es less than or equal to 10 cm(2)) a local recurrence rate of 2.2% was
observed, both after electron beam therapy and after superficial x-ra
y therapy. Tumor size and previous treatment proved to be important pr
ognostic factors with regard to control rate, The well-fractionated el
ectron beam therapy yielded better cosmetic results than the large fra
ction superficial x-ray therapy. Conclusion: Electron beam treatment i
s not inferior to superficial x-ray treatment and even better for larg
er tumors, The inferior results of electron beam therapy reported in l
iterature might be due to technical factors, which are discussed.