For patients with recurrent operable liver metastases from colorectal
cancer operative resection is the only chance of getting rid of their
tumorous disease for a longer time. As there are not therapeutic alter
natives more and more authors are reporting on repeated resections of
liver metastases. From 1986 to 1994 we performed 12 recurrent liver re
sections with curative intent in 8 patients suffering from liver metas
tases of colorectal cancer: 4 synchronous and 4 metachronous metastase
s were removed, the primary procedure being anatomic hemihepatectomy i
n 5 cases and segmentectomy or bisegmentectomy in 3 cases. The mean ti
me interval between the first and the second resections was 14 (4-23)
months. Two patients underwent 4 consecutive liver resections because
of recurrent metastases. In these cases the interval between the secon
d, third and fourth procedures was 10 months. The postoperative compli
cation rate was 16% and not a single patient died in hospital. Three p
atients died an average of 28 (9-54) months after the last liver resec
tion, and the other 5 patients are still alive after an average of 14
(4-28) months: 3 are free of tumor and 2 have recurrent metastases in
the liver. Compared with untreated or only locally treated cases, pati
ents in whom operative risk is low can achieve prolonged survival time
s after resections of colorectal metastases to the liver.