SOME INSECT ALLATOREGULATING PEPTIDES - SYNTHETIC AND BIOLOGICAL STUDIES

Authors
LOMBARSKASLIWINSKA D ROSINSKI G BARTOSZBECHOWSKI H STRONCZAK W PLECH A SOBTKA W KONOPINSKA D
Citation
D. Lombarskasliwinska et al., SOME INSECT ALLATOREGULATING PEPTIDES - SYNTHETIC AND BIOLOGICAL STUDIES, Bulletin of the Polish Academy of Sciences. Chemistry, 43(1), 1995, pp. 33-40
Citations number
9
Categorie Soggetti
Chemistry
Journal title
Bulletin of the Polish Academy of Sciences. Chemistry → ACNP
ISSN journal
02397285
Volume
43
Issue
1
Year of publication
1995
Pages
33 - 40
Database
ISI
SICI code
0239-7285(1995)43:1<33:SIAP-S>2.0.ZU;2-I
Abstract
Allatotropin (1) ys-Asn-Val-Glu-Met-Met-Thr-Ala-Arg-Gly-Phe-amide), al latostatin-I (2) er-Gly-Ala-Gln-Arg-Leu-Tyr-Gly-Phe-Gly-Leu-amide), pe nta- and heptapeptide fragments of allatostatins (I-IV) such as: Tyr-X -Phe-Gly-Leu-amide (3-5) and Arg-Leu-Tyr-X-Phe-Gly-Leu-amide (6-8) (wh ere X = Gly, Ala, Ser) were synthesized by solid-phase method. Their b iological effects in respect to insect - Tenebrio molitor (in vitro an d in vivo) and behavioural activity in rats were examined.