We report a case of acute hepatitis in a 28-year-old male with acquire
d rubella infection. Serological tests revealed acute rubella virus in
fection and ruled out infection by other common viruses, including typ
e A and type B hepatitis viruses. The patient showed not only marked i
ncrease of lactate dehydrogenase (LDH) activity, with only slight live
r dysfunction, but also platelet and kidney injury, suggesting systemi
c rubella virus infection. Because the liver dysfunction was slight, l
iver biopsy was not performed. When a patient has mild, transient hepa
titis accompanied by high LDH activity in comparison with both asparta
te aminotransferase (AST) and alanine aminotransferase (ALT) levels, w
e should take a common viral infection such as rubella into considerat
ion when making a diagnosis.