CYCLOSPORINE-INDUCED WORSENING OF HEPATIC-DYSFUNCTION IN A PATIENT WITH CROHNS-DISEASE AND ENTEROCUTANEOUS FISTULA

Cyclosporine recently has become part of the treatment regimen for pat ients with refractory inflammatory bowel disease, though it is still c onsidered investigational for that purpose. However, little attention has been given to the potential hepatotoxicity associated with cyclosp orine administration. This can be especially significant in patients w ith preexisting abnormalities of liver function, including those induc ed by total parenteral nutrition.