PRIMARY ANGIOSARCOMA OF THE SPLEEN - A CASE-REPORT AND REVIEW OF THE LITERATURE

We describe a 47-year-old man with shoulder pain, multiple bony lesion s, and a 1-cm lesion in the spleen. T-1 facetectomy revealed a poorly differentiated malignant neoplasm. Several months after chemotherapy, multiple splenic lesions were found by computed tomography and liver-s pleen scan. A splenectomy showed a malignant spindle-cell neoplasm for ming irregular vascular spaces. Tumor cells were positive for factor V III-related antigen and vimentin. This patient died of extensive metas tases from this primary angiosarcoma of the spleen. Splenic angiosarco ma is a rare neoplasm that often has a cryptic presentation and a dism al prognosis.