Acute pancreatitis has a mortality of about 10%: this figure has not c
hanged over the last 20 years. A retrospective audit of fatal acute pa
ncreatitis was performed in a teaching hospital with a catchment popul
ation of about 750 000 patients to examine patient charactistics. Usin
g Hospital Activity Analysis code 577.0, all fatal cases of acute panc
reatitis were studied in a six-year period 1987-93. Additionally, all
post mortem diagnoses of acute pancreatitis were traced. The overall p
ost mortem rate in Nottingham at the time of the study was about 35%.
All available records, X-ray and biochemical data were studied and app
ropriate information recorded and analysed for 65 fatal cases. Only 15
% were post mortem diagnoses, lower than in previous series; 72% had r
espiratory and 67% had renal complications. Only 34% had been admitted
to the intensive care unit. A third of patients had had surgery; 67%
of these was some form of external drainage. Of the 14 patients with p
roven gallstone pancreatitis only three had endoscopic retrograde chol
angiopancreatography; 42% of patients had idiopathic disease. Not all
the patients diagnosed ante mortem had the full biochemical predicted
severity criteria analysed: pO(2) and calcium analysis was performed i
n about 80%. Premortem diagnoses of pancreatitis was achieved more fre
quently than in other comparable series.