The MAP kinases are important mediators of intracellular signal transd
uction, and regulation involving them has been implicated in a wide va
riety of physiological processes. Studies in yeast and mammals have id
entified subgroups of these enzymes that have different substrate spec
ificities and are regulated by different extracellular stimuli. Recent
ly, studies in plants have revealed that there is a similar divergence
of MAP kinase functions, and pathways involving MAP kinases have been
linked to signal transduction caused by wounding, pathogens and abiot
ic stresses, as well as the plant hormones abscisic acid, auxin and et
hylene. Thus, pathways involving MAP kinases are a common mechanism fo
r signal transduction in all eukaryotes, and have been adapted to coup
le distinct stimuli to specific physiological responses.