Z. Arfeen et al., A DOUBLE-BLIND RANDOMIZED CONTROLLED TRIAL OF GINGER FOR THE PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING, Anaesthesia and intensive care, 23(4), 1995, pp. 449-452
Citations number
21
Categorie Soggetti
Anesthesiology,"Emergency Medicine & Critical Care
The efficacy of ginger for the prevention of postoperative nausea and
vomiting was studied in a double-blind, randomized, controlled trial i
n 108 ASA 1 or 2 patients undergoing gynaecological laparoscopic surge
ry under general anaesthesia. Patients received oral placebo ginger BP
0.5g or ginger BP 1.0g, ah with oral diazepam premedication, one hour
prior to surgery. Patients were assessed at three hours postoperative
ly. The incidence of nausea and vomiting increased slightly but nonsig
nificantly with increasing dose of ginger. The incidence of moderate o
r severe nausea was 22, 33 and 36%, while the incidence of vomiting wa
s 17, 14 and 31% in groups receiving 0, 0.5 and 1.0g ginger, respectiv
ely (odds ratio per 0.5g ginger 1.39 for nausea and 1.55 for vomiting)
. These results were essentially unchanged when adjustment was made fo
r concomitant risk factors. We conclude that ginger BP in doses of 0.5
or 1.0 gram is ineffective in reducing the incidence of postoperative
nausea and vomiting.