ASPERGILLUS KERATITIS AFTER RADIAL KERATOTOMY

PURPOSE/METHODS: A case of severe Aspergillus keratitis after radial k eratotomy manifested as a discrete midstromal infiltrate along a radia l incision, Despite aggressive treatment with topical amphotericin B a nd oral itraconazole, the patient: required a therapeutic penetrating keratoplasty. RESULTS/CONCLUSIONS: Histopathologic examination disclos ed a corneal ulcer with numerous septate, branching hyphae throughout the stroma, and marked stromal necrosis. Aspergillus species should be included among the microbial pathogens responsible for infectious ker atitis after radial keratotomy. If infectious keratitis is suspected, comprehensive cultures for bacteria and fungi should be obtained.