There is a wealth of data suggesting that microtubules and associated
motor proteins play important roles in orchestrating membrane traffic
within higher eukaryotes, with myosins and actin filaments fulfilling
similar functions in organisms such as fungi, algae and plants. In add
ition, evidence is accumulating that both cytoskeletal systems can co-
operate within one cell. Recent studies have highlighted how individua
l motor proteins can act at multiple steps in the membrane-traffic pat
hways, and in contrast, how more than one motor type may be involved i
n each transport step and in generating organelle morphology.