Ef. Schipper et al., FEASIBILITY OF OPTICAL WAVE-GUIDE IMMUNOSENSORS FOR PESTICIDE DETECTION - PHYSICAL ASPECTS, Sensors and actuators. B, Chemical, 24(1-3), 1995, pp. 90-93
The feasibility of detecting small molecules such as pesticides using
optical evanescent-wave sensors is discussed with emphasis on the Mach
-Zehnder sensor and a newly developed sensor called a 'critical' senso
r. For direct detection of an estimated average pesticide layer growth
of 2X10(-4) nm, the sensitivity of the Mach-Zehnder sensor is almost
adequate (1X10(-3) nm within one hour), whereas that of the 'critical'
sensor (2X10(-2) nm) is not sufficient. However, the simplicity of th
is latter sensor is very attractive. Results of alpha-hSA/hSA immunore
action experiments obtained with this last type of sensor are presente
d.