CONSERVATIVE TREATMENT OF ENDOMETRIAL CANCER PERMITTING SUBSEQUENT TRIPLET PREGNANCY

We report on a 28-year-old woman who received conservative treatment o f endometrial carcinoma by curettage and progestins. After regression of endometrial lesions the patient's infertility was treated by gamete intrafallopian transfer (GIFT), Intact triplet pregnancy was diagnose d 3 weeks later. The patient was delivered of three infants by caesare an section following premature rupture of membranes at 30 weeks of ges tation. Subsequent standard treatment of endometrial cancer by abdomin al hysterectomy and bilateral salpingo-oophorectomy after 4 weeks reve aled no clinical or histological evidence of persistent carcinoma. One year after surgery the patient remained without evidence of disease. We believe that individualized cancer therapy may be safely performed in carefully selected cases. (C) 1995 Academic Press, Inc.