PRIMARY FALLOPIAN-TUBE ADENOCARCINOMA - CLINICAL COMPLETE RESPONSE AFTER SALVAGE TREATMENT WITH HIGH-DOSE PACLITAXEL

This Case Report describes a patient with primary fallopian tube cance r who had a late recurrence of pelvic disease following adjuvant chemo therapy for early-stage disease. Secondary cytoreductive surgery was s uboptimal. The bulky residual disease was refractory to platinum-based therapy. Extention of the disease to the retroperitoneum resulted in obstructed venous return, ureteral obstruction, and renal infection. T he latter necessitated a third laparotomy and a nephrectomy. Upon reco very from surgery and failure of platinum reinduction, the patient was treated with high-dose paclitaxel. The large pelvic mass regressed ra pidly and completely. Current chemotherapy for fallopian tube cancer i s briefly reviewed. (C) 1995 Academic Press, Inc.