We performed a 2-year microbiological study of specimens of sinus flui
d recovered from patients with suspected nosocomial sinusitis in six i
ntensive care units. Over that period, 103 cases of sinusitis were doc
umented by positive culture. The number of cases varied widely from on
e unit to another and was particularly high in the neurosurgical unit.
Cultures were often polymicrobial. The main pathogens were Staphyloco
ccus aureus, Pseudomonas aeruginosa, Acinetobacter baumannii and Enter
obacteriaceae. Streptococcus pneumoniae and Haemophilus influenzae wer
e far less frequently isolated. Anaerobes and yeasts were often associ
ated with aerobic bacteria. The pathogen involved was also recovered f
ront bronchopulmonary samples in 50 patients and from blood cultures i
n seven patients.