TRANS-FATTY-ACIDS AND THEIR EFFECTS ON LIPOPROTEINS IN HUMANS

Trans fatty acids raise plasma low-density lipoprotein (LDL) cholester ol levels in volunteers when exchanged for cis unsaturated fatty acids in the diet. In addition, trans fatty acids may lower high-density li poprotein (HDL) cholesterol levels and raise triglyceride and lipoprot ein(a) levels in plasma. Trans and cis unsaturated fatty acids are thu s not equivalent, and diets aimed at reducing the risk of coronary hea rt disease should be low in both trans and saturated fatty acids.