Objective: To consider the role of software in system operation, contr
ol and automation, and attempts to define intelligence. Methods and Re
sults: Artificial intelligence (AI) is characterized by its ability to
deal with incomplete and imprecise information and to accumulate know
ledge. Expert systems, building on standard computing techniques, depe
nd heavily on the domain experts and knowledge engineers that have pro
grammed them to represent the real world. Neural networks are intended
to emulate the pattern-recognition and parallel processing capabiliti
es of the human brain and are taught rather than programmed. The futur
e may lie in a combination of the recognition ability of the neural ne
twork and the rationalization capability of the expert system. In the
second part of this paper, examples are given of applications of AI in
stand-alone systems for knowledge engineering and medical diagnosis a
nd in embedded systems for failure detection, image analysis, user int
erfacing, natural language processing, robotics and machine learning,
as related to clinical laboratories. Conclusion: AI constitutes a coll
ective form of intellectual property, and that there is a need for bet
ter documentation, evaluation and regulation of the systems already be
ing used widely in clinical laboratories.