LANGERHANS CELL HISTIOCYTOSIS ASSOCIATED WITH ELEVATION OF ANGIOTENSIN-CONVERTING ENZYME LEVELS - CASE-REPORT

Authors
ROSENSTEIN ED ESKOW RN LEDERMAN DA KRAMER N
Citation
Ed. Rosenstein et al., LANGERHANS CELL HISTIOCYTOSIS ASSOCIATED WITH ELEVATION OF ANGIOTENSIN-CONVERTING ENZYME LEVELS - CASE-REPORT, The American journal of the medical sciences, 310(2), 1995, pp. 65-67
Citations number
16
Categorie Soggetti
Medicine, General & Internal
Journal title
The American journal of the medical sciences → ACNP
ISSN journal
00029629
Volume
310
Issue
2
Year of publication
1995
Pages
65 - 67
Database
ISI
SICI code
0002-9629(1995)310:2<65:LCHAWE>2.0.ZU;2-Y
Abstract
The authors describe a 22-year-old man with osteolytic mandibular and maxillary lesions, Biopsy substantiated the presence of Langerhans cel l histiocytosis (eosinophilic granuloma). Levels of serum angiotensin- converting enzyme (ACE) were elevated repeatedly. After definitive the rapy with excision and bone grafting, ACE levels returned to normal. T he role of histiocytes in ACE production is discussed. Langerhans cell histiocytosis should be considered in the diagnosis of conditions occ urring with elevation of serum ACE levels and clinical findings simila r to sarcoidosis.