DIASTEREOSELECTIVE SYNTHESIS OF VINYLMORPHOLINES BY PALLADIUM-CATALYZED TANDEM ALLYLIC SUBSTITUTIONS USING ENANTIOPURE AMINOALCOHOLS AS BIFUNCTIONAL NUCLEOPHILES

Authors
THOREY C WILKEN J HENIN F MARTENS J MEHLER T MUZART J
Citation
C. Thorey et al., DIASTEREOSELECTIVE SYNTHESIS OF VINYLMORPHOLINES BY PALLADIUM-CATALYZED TANDEM ALLYLIC SUBSTITUTIONS USING ENANTIOPURE AMINOALCOHOLS AS BIFUNCTIONAL NUCLEOPHILES, Tetrahedron letters, 36(31), 1995, pp. 5527-5530
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
31
Year of publication
1995
Pages
5527 - 5530
Database
ISI
SICI code
0040-4039(1995)36:31<5527:DSOVBP>2.0.ZU;2-U
Abstract
Enantiopure vinylmorpholines have been prepared by a diastereoselectiv e disubstitution (de up to 92%) of (Z) ROCH(2)CH=CHCH(2)OR (R = Ac, CO (2)Me) by aminoalcohols in the presence of palladium catalysts.