A NOVEL BLEOMYCIN MODEL-COMPOUND BEARING HYDROPHILIC STERIC FACTOR EXHIBITED HIGH OXYGEN ACTIVATING CAPACITY

Authors
KOHDA J SHINOZUKA K SAWAI H
Citation
J. Kohda et al., A NOVEL BLEOMYCIN MODEL-COMPOUND BEARING HYDROPHILIC STERIC FACTOR EXHIBITED HIGH OXYGEN ACTIVATING CAPACITY, Tetrahedron letters, 36(31), 1995, pp. 5575-5578
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
31
Year of publication
1995
Pages
5575 - 5578
Database
ISI
SICI code
0040-4039(1995)36:31<5575:ANBMBH>2.0.ZU;2-P
Abstract
The bleomycin (BLM) model compound bearing hydrophilic steric factor w as synthesized and the physicochemical properties of the metal complex es were studied. Iron complex of the model compound exhibited BLM like reversible redox cycle and higher oxygen activating activity compared to the corresponding model compound bearing hydrophobic steric factor .