Palmaris brevis spasm syndrome is a rare and benign condition of local
ised muscular hyperactivity. In five men, the hypothenar eminence unde
rwent spontaneous, irregular, tonic contractions of the palmaris brevi
s muscle. An EMG showed spontaneous high frequency discharges of norma
l motor units, without evidence of neuropathy or of nerve compression.
This syndrome resembles other restricted muscle hyperactivity syndrom
es although there are some differences. Curiously, the palmaris brevis
muscle is not under voluntary control. The mechanism of the syndrome
could be an ephaptic transmission possibly secondary to the transient
and repeated stretching of the ulnar nerve superficial branch. In one
patient a root compression was the probable origin.