QUANTITATIVE SPECT IMAGING - A REVIEW AND RECOMMENDATIONS BY THE FOCUS COMMITTEE OF THE SOCIETY-OF-NUCLEAR-MEDICINE COMPUTER AND INSTRUMENTATION COUNCIL

This article is a review of the physics principles, instrumentation an d reconstruction methods behind SPECT imaging. Particular attention is paid to the mechanisms that can significantly affect the accuracy of a SPECT image. We describe instrumentation advances and reconstruction methods used to correct images to improve image quality and produce q uantitative images. The clinical importance of improved image quality and quantitation are also reviewed.