A NONPEPTIDIC AGONIST LIGAND OF THE HUMAN C5A RECEPTOR - SYNTHESIS, BINDING-AFFINITY OPTIMIZATION AND FUNCTIONAL-CHARACTERIZATION

Authors
DELASZLO SE ALLEN EE LI B ONDEYKA D RIVERO R MALKOWITZ L MOLINEAUX C SICILIANO SJ SPRINGER MS GREENLEE WJ MANTLO N
Citation
Se. Delaszlo et al., A NONPEPTIDIC AGONIST LIGAND OF THE HUMAN C5A RECEPTOR - SYNTHESIS, BINDING-AFFINITY OPTIMIZATION AND FUNCTIONAL-CHARACTERIZATION, Bioorganic & medicinal chemistry letters, 7(2), 1997, pp. 213-218
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
2
Year of publication
1997
Pages
213 - 218
Database
ISI
SICI code
0960-894X(1997)7:2<213:ANALOT>2.0.ZU;2-K
Abstract
The structural optimization for binding affinity and attempted modific ation of agonist function of a nonpeptide ligand of the human C5a rece ptor is described. (C) 1997, Elsevier Science Ltd.