Clinical features, diagnosis and treatment of 286 women whose high vag
inal swabs (HVS) submitted by their general practitioners showed pure,
heavy growth of Staphylococcus aureus, beta haemolytic streptococci g
roups A, C or G, Streptococcus milleri, Streptococcus pneumoniae or Ha
emophilus influenzae were analysed. Women with group A, C and G strept
ococci frequently had clinical vulvovaginitis and although the numbers
were too small for statistical confirmation, S. pneumoniae and H. inf
luenzae appeared to cause clinical disease as well. The association of
S. aureus or S. milleri with clinical vulvovaginitis was much less co
nvincing. It seems relevant for laboratories to report sensitivities f
or group A, C and C streptococci. Further research is needed to determ
ine the pathogenicity of S. pneumoniae and H. influenzae.