R. Lisbona et al., SUPINE AND PRONE SPECT TC-99M MIBI MYOCARDIAL PERFUSION IMAGING FOR DIPYRIDAMOLE STUDIES, Clinical nuclear medicine, 20(8), 1995, pp. 674-677
Aartifactual inferior wall defects of perfusion are a source of freque
nt concern during Tl-201 exercise stress redistribution SPECT imaging
in the supine position. These artifactual changes also affect Tc-99m s
estamibi dipyridamole myocardial perfusion studies with supine SPECT y
ielding a specificity of only 58% for right coronary artery (RCA) dise
ase. Complementary SPECT prone imaging will enhance this specificity f
or inferior wall abnormalities to 79% (P < 0.05) and is recommended fo
r more accurate assessment of RCA stenosis, whether the patient challe
nge is pharmacological or by exercise.