B. Pfausler et al., MULTIMODAL THERAPY IN LIFE-THREATENING CEREBRAL LUPUS-ERYTHEMATOSUS -THE BENEFIT OF CEREBROSPINAL-FLUID PHERESIS, International archives of allergy and immunology, 107(4), 1995, pp. 592-594
A 27-year-old female patient with severe cerebral systemic lupus eryth
ematosus did not respond to conventional therapy, including high-dose
corticosteroids and high-dose pulsed cyclophosphamide therapy. Cerebro
spinal fluid filtration (pheresis) led to rapid and lasting neurologic
al improvement and clinical cure.