H. Arai et al., COULOMETRIC ELECTROCHEMICAL DETECTION OF PHOSPHOLIPID HYDROPEROXIDES BY HIGHPERFORMANCE LIQUID-CHROMATOGRAPHY, Bioscience, biotechnology, and biochemistry, 61(1), 1997, pp. 191-193
A technique for the sensitive and convenient determination of phosphat
idylcholine hydroperoxides was developed that uses coulometric electro
chemical detection in a high-performance liquid chromatographic analys
is, The detection limit for phosphatidylcholine hydroperoxides by this
method was 20 pmol at a signal-to-noise ratio of 3, The glutathione-d
ependent phospholipid hydroperoxide-reducing activity of fresh human p
lasma was ascertained by this method.