S. Hori, A JAPANESE PHASE-III MULTICENTER COMPARISON OF IOTROLAN-280 WITH IOPAMIDOL-300 IN PERIPHERAL ARTERIOGRAPHY, European radiology, 5, 1995, pp. 24-29
Iotrolan 280 was compared with iopamidol 300 for safety and efficacy i
n peripheral arteriography in a randomized multicenter study of 148 pa
tients. Both contrast agents provided good visualization with no stati
stical difference between them. Pain and heat sensations following iot
rolan were milder than after iopamidol. Adverse events occurred in thr
ee patients receiving iotrolan and four patients receiving iopamidol,
with no statistical difference. The clinical value of iotrolan 280 was
judged to be better than iopamidol 300 in peripheral arteriography on
the basis of reduced pain and heat sensations.