Jm. Failla et Md. Linden, THE ACUTE PATHOLOGICAL-CHANGES OF PAINT-INJECTION INJURY AND CORRELATION TO SURGICAL-TREATMENT - A REPORT OF 2 CASES, The Journal of hand surgery, 22A(1), 1997, pp. 156-159
The early histologic changes of digital tissues after paint-injection
injury support the urgent need to remove all contaminated tissue. Pain
t causes immediate tissue necrosis on contact and then incites an imme
diate necrotizing inflammatory reaction that persists if the tissues a
re not completely debrided. Early histopathologic changes include Vess
el thrombosis, tissue necrosis, and acute necrotizing inflammatory inf
iltrate, all occuring only hours after injection injury. In light of t
hese histologic changes, if paint cannot be completely removed from di
gital arteries in an attempt to salvage the finger, then the wound sho
uld be left open and the finger monitored for further necrosis in resp
onse to the retained paint.