A RELATIVELY SMALL 5' REGULATORY REGION OF ESTERASE-S GENE OF DROSOPHILA-VIRILIS DETERMINES THE SPECIFIC EXPRESSION AS REVEALED IN TRANSGENIC EXPERIMENTS

Authors
KOROCHKIN LI PANIN VM PAVLOVA GV KOPANTSEVA MR SHOSTAK NG BASHKIROV VN GABITOVA LB SERGEEV PV
Citation
Li. Korochkin et al., A RELATIVELY SMALL 5' REGULATORY REGION OF ESTERASE-S GENE OF DROSOPHILA-VIRILIS DETERMINES THE SPECIFIC EXPRESSION AS REVEALED IN TRANSGENIC EXPERIMENTS, Biochemical and biophysical research communications, 213(1), 1995, pp. 302-310
Citations number
17
Categorie Soggetti
Biology,Biophysics
Journal title
Biochemical and biophysical research communications → ACNP
ISSN journal
0006291X
Volume
213
Issue
1
Year of publication
1995
Pages
302 - 310
Database
ISI
SICI code
0006-291X(1995)213:1<302:ARS5RR>2.0.ZU;2-2
Abstract
Expression of the esterase S gene of Drosophila virilis was studied in transgenic experiments. Truncated genomic copy of this gene including 400 bp of 5' regulatory region was integrated into the genome of Dros ophila melanogaster. The products of the transferred gene were detecte d. It was found that strict temporal and tissue specificity of the est erase S gene expression is conserved in transformed flies. The results suggest that this specificity is evidently determined by the regulato ry region of the esterase S gene and controlled by cis mechanism. (C) 1995 Academic Press, Inc.