IN-3-YL)-2-(1-METHYL-1H-INDOL-3-YL)-2-OXOACETAMIDE - A HIGH-AFFINITY 5-HT3 RECEPTOR PARTIAL AGONIST

Authors
CLARK RD MUCHOWSKI JM WEINHARDT KK DILLON MP LEE CH BLEY KR BONHAUS DW WONG EHF EGLEN RM
Citation
Rd. Clark et al., IN-3-YL)-2-(1-METHYL-1H-INDOL-3-YL)-2-OXOACETAMIDE - A HIGH-AFFINITY 5-HT3 RECEPTOR PARTIAL AGONIST, Bioorganic & medicinal chemistry letters, 5(16), 1995, pp. 1853-1856
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
16
Year of publication
1995
Pages
1853 - 1856
Database
ISI
SICI code
0960-894X(1995)5:16<1853:I-AH5>2.0.ZU;2-G
Abstract
The enantiomers of the indolyl-2-oxoacetamide 5 were found to have 5-H T3 receptor partial agonist activity with(R)-5 having higher potency t han (S)-5.