Clear-cell sarcoma is a rare tumor that arises in association with ten
dons and aponeuroses. Although it shares with malignant melanoma sever
al histologic and ultrastructural features, it has a clinical course d
ifferent from that of conventional melanomas. A case of clear-cell sar
coma studied by immunoscintigraphy with Tc-99m-iabeled F(ab')2 fragmen
ts of the monoclonal antibody 225.28 S is reported.