SYNTHESIS OF SOME 2-[(5-METHOXY-1-METHYL)INDOL-2-YL]ETHYLAMINES AS SELECTIVE INHIBITORS OF MONOAMINE OXIDASE-A AND OXIDASE-B

Citation
Ef. Alvarez et al., SYNTHESIS OF SOME 2-[(5-METHOXY-1-METHYL)INDOL-2-YL]ETHYLAMINES AS SELECTIVE INHIBITORS OF MONOAMINE OXIDASE-A AND OXIDASE-B, Anales de quimica, 90(7-8), 1994, pp. 379-386
Citations number
14
Categorie Soggetti
Chemistry
Journal title
ISSN journal
11302283
Volume
90
Issue
7-8
Year of publication
1994
Pages
379 - 386
Database
ISI
SICI code
1130-2283(1994)90:7-8<379:SOS2AS>2.0.ZU;2-7
Abstract
We report the synthesis of some derivatives of 2-[(5-methoxy-1-methyl) indol-2-yl]ethylamine. These compounds (14-18) were obtained by aminat ion of -methoxy-1-methyl)indol-2-yl]ethylmethanesulfonate (12) IC50 va lues for the inhibition of MAO-A and B from rat liver are reported.