ASYMMETRIC-SYNTHESIS OF L-PHENYLAMINO ACI DS

Authors
CATIVIELA C DEVILLEGAS MDD GALVEZ JA LAPENA Y
Citation
C. Cativiela et al., ASYMMETRIC-SYNTHESIS OF L-PHENYLAMINO ACI DS, Anales de quimica, 90(7-8), 1994, pp. 432-437
Citations number
14
Categorie Soggetti
Chemistry
Journal title
Anales de quimica → ACNP
ISSN journal
11302283
Volume
90
Issue
7-8
Year of publication
1994
Pages
432 - 437
Database
ISI
SICI code
1130-2283(1994)90:7-8<432:AOLAD>2.0.ZU;2-#
Abstract
A new synthetic strategy to obtain alpha-phenylamino acids in enantiom erically pure form is described. The new route is based on the highly diastereoselective alkylation of (1S,2R,4R)-10-dicyclohexylsulfamoylis obornyl 2-phenylcianoacetate and subsequent Curtius type rearrangement of the alkylated compound with total retention of configuration.