Multidrug-resistant pathogens such as enterococci, coliforms and pseud
omonads are becoming endemic in many units caring for neutropenic pati
ents, probably because of the extensive use of prophylaxis and broad-s
pectrum therapy. Further studies of febrile episodes in neutropenia in
dicate that preventive and therapeutic regimens, such as quinolone pro
phylaxis and empirical monotherapy, can safely be tailored for specifi
c risk groups to a greater extent than before. The past year has seen
an increasing emphasis in the literature on cost control in the treatm
ent of neutropenic patients.