We report a 75-year-old man with a fulminant rosacea-like eruption, su
ggestive of demodicidosis. Multiple Demodex folliculorum mites were fo
und in facial scales and pustules and, on histological examination, in
the infundibulum of pilosebaceous follicles and in the dermis, Intrad
ermal mites were surrounded either by polymorphonuclear granulocytes a
nd histiocytes, or by a granulomatous infiltrate containing foreign-bo
dy giant cells, which had phagocytosed the parasites. Complete recover
y, with disappearance of facial mites, was achieved by treatment with
a combination of oral and topical metronidazole, although this drug is
not known to be miticidal.