SEVERE DIARRHEA DUE TO COKEROMYCES-RECURVATUS IN A BONE-MARROW TRANSPLANT RECIPIENT

Cokeromyces recurvatus, a sporangiola-forming dimorphic fungus, is a r are cause of urogenital infection in humans. We report here a case of severe watery diarrhea due to C. recurvatus, which was treated success fully with high-dose oral nystatin therapy. We speculate that our pati ent was probably predisposed to infections due to opportunistic organi sms, such as C. recurvatus, because of post-transplantation immunosupp ression. To our knowledge, our patient represents the first documented case of diarrhea due to C. recurrvatus in man, and this case highligh ts the potential pathogenic capability of this opportunistic organism in immunosuppressed patients.