DENTAL PROPERTIES OF ANTISEPTIC THROAT LOZENGES FORMULATED WITH SUGARS OR LYCASIN

Authors
Citation
Th. Grenby, DENTAL PROPERTIES OF ANTISEPTIC THROAT LOZENGES FORMULATED WITH SUGARS OR LYCASIN, Journal of clinical pharmacy and therapeutics, 20(4), 1995, pp. 235-241
Citations number
13
Categorie Soggetti
Pharmacology & Pharmacy
ISSN journal
02694727
Volume
20
Issue
4
Year of publication
1995
Pages
235 - 241
Database
ISI
SICI code
0269-4727(1995)20:4<235:DPOATL>2.0.ZU;2-F
Abstract
Thirteen different formulations of throat lozenges were examined for t heir acidity, demineralizing action on hydroxylapatite, and fermentabi lity by human dental plaque micro-organisms, Their flavouring acids ga ve them low pH values in the range 2.6-3.7, leading to the dissolution of calcium and phosphorus from hydroxylapatite. The combination of an tiseptics and flavouring acids in the lozenges inhibited microbial gro wth and metabolism. In the absence of any antiseptics and flavouring a cids, the growth and metabolic activity of cultures of plaque micro-or ganisms were significantly greater on sucrose + glucose lozenges than on a new Lycasin formulation.